ZFP106 Products

Description

Zinc finger protein homolog 106 (ZFP106) is a C2H2-type zinc finger protein that also contains 2 WD repeats. ZFP106 is highly expressed in striated muscle, brown fat, and developing brain and is regulated by myogenin and nuclear respiratory factor-1 (NRF-1). ZFP106 localizes to the nucleus in association with nucleolar transcriptional machinery. The WD40 repeat in ZFP106 appears to facilitate targeting of ZFP106 to the nucleolus and to mediate the interaction between ZFP106 and testis-specific gene 118 (TSF118). A two-hybrid screen has identified testis-specific Y-encoded-like protein (TSPYL) as a ZFP106 interacting protein. These data suggest an important role for ZFP106 in testis development.

Bioinformatics

Entrez	64397 Human
Uniprot	NP_071918.1 Human
Product By Gene ID	64397
Alternate Names	DKFZp451A239 Zfp-106 SH3BP3 zinc finger protein 106 homolog Zinc finger protein 474 zfp-106 SH3-domain binding protein 3 ZNF474FLJ45841 FLJ34610 zinc finger protein 106 homolog (mouse)

Diseases related to ZFP106

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Congenital Abnormality
Sudden Infant Death Syndrome
Diabetes Mellitus

Pathways for ZFP106

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Nucleosome Assembly
Translation
Insulin Receptor Signaling Pathway

Bioinformatics Tool for ZFP106

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