XPF Products

Antibodies
XPF Antibody (4E11)
XPF Antibody (4E11)
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
XPF Antibody
XPF Antibody
NB100-60679
Species: Hu, Primate, Rhesus Macaque
Applications: WB, ELISA, IHC, IHC-P, IP
Host: Rabbit Polyclonal
Lysates
XPF Overexpression Lysate (Na ...
XPF Overexpression Lysate (Native)
NBL1-10322
Applications: WB
RNAi
XPF RNAi
XPF RNAi
H00002072-R01
Species: Hu

Description

XPF/ERCC4 is suggested to play a role in the repair of DNA double-strand breaks (DSB), homologous recombination, and gene conversion via single-strand annealing (SSA). XPF/ERCC4 is an endonuclease that incises 5-prime DNA. Defects in XPF/ERCC4 cause xeroderma pigmentosum VI (XP6) an autosomal recessive disease characterized by hypersensitivity to sunlight and a predisposition to skin cancer as well as neurological abnormalities. Defects in XPF/ERCC4 are also responsible for XFE progeroid syndrome, a syndrome characterized by dwarfism, cachexia, and microcephaly.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 2072
Alternate Names
  • EC 3.1
  • DNA excision repair protein ERCC-4
  • xeroderma pigmentosum, complementation group F
  • ERCC11
  • XPFcomplementing defective, in Chinese hamster
  • DNA repair protein complementing XP-F cells
  • excision repair cross-complementing rodent repair deficiency, complementationgroup 4

Research Areas for XPF

Find related products by research area and learn more about each of the different research areas below.

Cancer
DNA Repair
Nucleotide Excision Repair

PTMs for XPF

Learn more about PTMs related to XPF.

Methylation
Phosphorylation
Cleavage

Bioinformatics Tool for XPF

Discover related pathways, diseases and genes to XPF. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related XPF Blog Posts

Check out the latest blog posts on XPF.
NER Antibodies in Cancer Research
We at Novus Biologicals have over 230 products in our antibody catalog devoted to nucleotide excision repair. NER is a multi-stage sequential process involving over 30 proteins, all of which have been widely studied. Being the primary method to repair...    Read more.
Read more XPF related blogs.