XAB1 Products

Antibodies
XAB1 Antibody
XAB1 Antibody
NBP1-90072
Species: Hu, Mu, Rt, Mouse
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
XAB1 Antibody (3E1)
XAB1 Antibody (3E1)
H00011321-M01
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
XAB1 Antibody
XAB1 Antibody
NBP2-38332
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Antibody Pairs
XAB1 Antibody Pair
XAB1 Antibody Pair
H00011321-PW2
Species: Hu
Applications: WB, IP
Lysates
XAB1 Overexpression Lysate (D ...
XAB1 Overexpression Lysate (Denatu...
H00011321-T01
Species: Hu
Applications: WB
XAB1 Overexpression Lysate (N ...
XAB1 Overexpression Lysate (Native)
NBP2-10372
Applications: WB
Proteins
XAB1 Recombinant Protein Anti ...
XAB1 Recombinant Protein Antigen
NBP2-38332PEP
Species: Hu
Applications: AC
XAB1 Recombinant Protein Anti ...
XAB1 Recombinant Protein Antigen
NBP1-90072PEP
Species: Hu
Applications: AC
XAB1 Recombinant Protein
XAB1 Recombinant Protein
NBP1-98928
Species: Hu
Applications: PAGE
RNAi
XAB1 RNAi
XAB1 RNAi
H00011321-R01
Species: Hu

Description

The DNA methylation system is composed of methyl-CpG-binding proteins, as well as of DNA cytosine methyl transferases. Five methyl-CpG binding proteins were isolated: MeCP2, MBD1, MBD2, MBD3 and MBD4. MBD2 consists of two isoforms, MBD2a and MBD2b, which are generated from a single gene. MBD2a is a component of MeCP1, a large corepressor complex that represses transcription from densely methylated genes. Components of MeCP1 include MBD2, Mi-2, MTA2, MBD3 and HDAC1/2. MIZF and MBDin were isolated as proteins interacting with MBD2. MBDin, in turn, is identical to XPA binding protein 1 (XAB1). At the N erminus, the protein contains the consensus sequence for a GTP binding site. At the C terminus, the protein is characterized by an acidic domain containing a cluster of acidic amino acid residues. The transcriptional repression by MBD2 at methylated promoters is relieved by MBdin. XAB1 is expressed ubiquitously, and may be involved in nuclear localization of XPA.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 11321
Alternate Names
  • MBDin
  • MBD2-interacting protein
  • ATP(GTP)-binding protein
  • GTPase
  • ATPBD1A
  • XAB1FLJ51176
  • MBDINXPA binding protein 1
  • XPA-binding protein 1
  • GPN-loop GTPase 1

Diseases related to XAB1

Discover more about diseases related to XAB1.

Xeroderma Pigmentosum Complementation Group A
Xeroderma
Xeroderma Pigmentosum

Pathways for XAB1

View related products by pathway and learn more about each of the pathways below.

Transport
Localization
Nuclear Import
Nuclear Export
Nuclear Transport
Methylation
Dna Repair
Pigmentation
Nucleocytoplasmic Transport
Demethylation

Research Areas for XAB1

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction

PTMs for XAB1

Learn more about PTMs related to XAB1.

Methylation

Bioinformatics Tool for XAB1

Discover related pathways, diseases and genes to XAB1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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