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3669-WN) induces alkaline phosphatase production in the C3H10T1/2 mouse embryonic fibroblast in a dose-dependent manner (orange line). Alkaline Phosphatase Production elicited by Recombinant Mouse Wnt-9b (400 ng/mL) is neutralized (green line) by increasing concentrations of Rat Anti-Mouse Wnt-9b Monoclonal Antibody (Catalog # MAB36691). The ND50 is typically 125-750 ng/mL." class="big_lightbox" target="_blank">
Species: Mu Applications: B/N Host: Rat Monoclonal
The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. Study of its expression in the teratocarcinoma cell line NT2 suggests that it may be implicated in the early process of neuronal differentiation of NT2 cells induced by retinoic acid. This gene is clustered with WNT3, another family member, in the chromosome 17q21 region. [provided by RefSeq]