WASF1/WAVE1 Products

Antibodies
WASF1/WAVE1 Antibody
WASF1/WAVE1 Antibody
NB100-92239
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
WASF1/WAVE1 Antibody
WASF1/WAVE1 Antibody
NBP1-83018
Species: Hu, Mouse
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
WASF1/WAVE1 Antibody
WASF1/WAVE1 Antibody
AF5514
Species: Hu, Mu
Applications: WB
Host: Goat Polyclonal
Lysates
WASF1/WAVE1 Overexpression Ly ...
WASF1/WAVE1 Overexpression Lysate ...
NBL1-17775
Applications: WB
Proteins
WASF1/WAVE1 Partial Recombina ...
WASF1/WAVE1 Partial Recombinant Pr...
H00008936-Q01
Species: Hu
Applications: WB, ELISA, PA
WASF1/WAVE1 Recombinant Prote ...
WASF1/WAVE1 Recombinant Protein An...
NBP1-83018PEP
Species: Hu
Applications: AC

Description

WASP (for Wiskott-Aldrich syndrome protein), N-WASP are downstream effectors of Cdc42 that are implicated in actin polymerization and cytoskeletal organization. The WASP family also includes VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), which accumulate at focal adhesions and are also involved in the regulation of the actin cytoskeleton. The WAVE proteins are related to the WASP family proteins and are likewise involved in mediating actin reorganization downstream of the Rho family of small GTPases. The two protein homologs WAVE1 and WAVE2 specifically regulate membrane ruffling by inducing the formation of actin filament clusters in response to GTP binding and activating Rac. The WAVE proteins mediate this actin polymerization by cooperating with the Arp2/3 complex, a nucleation core, and thereby promoting the formation of actin filaments. WAVE1, which is also designated SCAR (for suppressor of cAR), is expressed primarily in the brain, while WAVE2 is widely expressed with the expression highest in peripheral blood leukocytes.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 8936
Alternate Names
  • wisk
  • Protein WAVE-1
  • KIAA0269WAVEhomology of dictyostelium scar 1
  • WAVE1FLJ31482
  • SCAR1WASP family protein member 1
  • Verprolin homology domain-containing protein 1
  • WAS protein family, member 1

Research Areas for WASF1/WAVE1

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific

PTMs for WASF1/WAVE1

Learn more about PTMs related to WASF1/WAVE1.

Phosphorylation
Dephosphorylation
Myristoylation

Bioinformatics Tool for WASF1/WAVE1

Discover related pathways, diseases and genes to WASF1/WAVE1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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