Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Am, Bv, Ca, Ch, Tr
Applications: WB, Simple Western, ICC/IF, IHC, Single-Cell Western
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Po, Bv, Ch
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. (provided by RefSeq)
Bioinformatics
| Entrez |
Mouse
Rat
Chicken
Human
|
| Uniprot |
Human
Human
Human
Chicken
Human
|
| Product By Gene ID |
7414 |
| Alternate Names |
- CMD1W
- CMH15
- metavinculin
- Metavinculin
- MVCL
- vinculin
|
![Western Blot Vinculin Antibody (728526) [Unconjugated]](http://images.novusbio.com/fullsize2/Vinculin_MAB6896_Western_Blot_11566.jpg)
![Immunohistochemistry Vinculin Antibody (728526) [Unconjugated]](http://images.novusbio.com/fullsize2/Vinculin_MAB6896_Immunohistochemistry_11621.jpg)
![Simple Western Vinculin Antibody (728526) [Unconjugated]](http://images.novusbio.com/fullsize2/Vinculin_MAB6896_Simple_Western_16408.jpg)
![Western Blot Vinculin Antibody (728526) [Unconjugated]](http://images.novusbio.com/fullsize/mab6896_human-mouse-rat-vinculin-mab-clone-728526-41202410482413.jpg)
![Western Blot Vinculin Antibody (728526) [Unconjugated]](http://images.novusbio.com/fullsize/mab6896_human-mouse-rat-vinculin-mab-clone-728526-41202410481138.jpg)
![Western Blot Vinculin Antibody (728526) [Unconjugated]](http://images.novusbio.com/fullsize/mab6896_human-mouse-rat-vinculin-mab-clone-728526-4120241048114.jpg)
![Simple Western Vinculin Antibody (728526) [Unconjugated]](http://images.novusbio.com/fullsize/mab6896_human-mouse-rat-vinculin-mab-clone-728526-30820241044559.jpg)
