Species: Hu, Mu
Applications: WB, Simple Western, ChIP, Func, GS, IHC, ChIP
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB
Host: Rabbit Monoclonal
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF
Host: Rabbit Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression
Bioinformatics
Entrez |
Mouse Human |
Uniprot |
Human Mouse Human |
Product By Gene ID |
23326 |
Alternate Names |
- Deubiquitinating enzyme 22
- EC 3.1.2.15
- EC 3.4.19.12
- KIAA1063ubiquitin carboxyl-terminal hydrolase 22
- KIAA1064
- ubiquitin specific peptidase 22
- ubiquitin specific peptidase 3-like
- ubiquitin specific protease 22
- ubiquitin thioesterase 22
- Ubiquitin thiolesterase 22
- ubiquitin-specific processing protease 22
- Ubiquitin-specific-processing protease 22
- USP3L
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