USP20 Products

Antibodies
USP20 Antibody
USP20 Antibody
NB100-1260
Species: Hu
Applications: WB, IHC, IHC-P, PEP-ELISA
Host: Goat Polyclonal
USP20 Antibody
USP20 Antibody
NBP1-82946
Species: Hu, Mu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
USP20 Antibody
USP20 Antibody
NB100-59837
Species: Hu
Applications: WB, IP
Host: Rabbit Polyclonal
Antibody Pairs
USP20 Antibody Pair
USP20 Antibody Pair
H00010868-PW1
Species: Hu
Applications: WB, IP
Lysates
USP20 Overexpression Lysate ( ...
USP20 Overexpression Lysate (Denat...
H00010868-T01
Species: Hu
Applications: WB
USP20 Overexpression Lysate ( ...
USP20 Overexpression Lysate (Native)
NBL1-17652
Applications: WB
USP20 Overexpression Lysate ( ...
USP20 Overexpression Lysate (Native)
NBL1-17651
Applications: WB
Proteins
Recombinant Human USP20 Prote ...
Recombinant Human USP20 Protein
H00010868-P01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human USP20 Prote ...
Recombinant Human USP20 Protein
H00010868-Q01
Species: Hu
Applications: WB, ELISA, PA
USP20 Recombinant Protein Ant ...
USP20 Recombinant Protein Antigen
NBP1-82946PEP
Species: Hu
Applications: AC
RNAi
USP20 RNAi
USP20 RNAi
H00010868-R02
Species: Hu
Applications: RNAi, RNAi SP
USP20 RNAi
USP20 RNAi
H00010868-R01
Species: Hu
Applications: RNAi, RNAi SP
USP20 RNAi
USP20 RNAi
H00010868-R03
Species: Hu
Applications: RNAi, RNAi SP

Description

Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 10868
Alternate Names
  • EC 3.4.19.12
  • LSFR3A
  • ubiquitin thioesterase 20
  • Ubiquitin-specific-processing protease 20
  • ubiquitin carboxyl-terminal hydrolase 20
  • Ubiquitin thiolesterase 20
  • pVHL-interacting deubiquitinating enzyme 2
  • Deubiquitinating enzyme 20
  • VHL-interacting deubiquitinating enzyme 2
  • ubiquitin specific protease 20
  • KIAA1003hVDU2
  • VDU2
  • ubiquitin specific peptidase 20

Research Areas for USP20

Find related products by research area and learn more about each of the different research areas below.

GPCR

PTMs for USP20

Learn more about PTMs related to USP20.

Ubiquitination

Bioinformatics Tool for USP20

Discover related pathways, diseases and genes to USP20. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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