Species: Hu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Ca, Pm
Applications: WB
Host: Mouse monoclonal
Species: Hu
Applications: WB, ICC/IF
Host: Mouse Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific processing protease 16 (USP16) is a member of this family. USP16 activity is cell cycle regulated via phosphorylation and participates in cell cycle control by influencing mitotic chromosome condensation and histone 2A (H2A) deubiquitination.
Bioinformatics
| Entrez |
Human |
| Uniprot |
Human Human Human Human Human Human Human Human Human Human Human |
| Product By Gene ID |
10600 |
| Alternate Names |
- Deubiquitinating enzyme 16
- EC 3.1.2.15
- EC 3.4.19.12
- human ubiquitin processing protease, EC 3.1.2.1510ubiquitin specific protease 16
- ubiquitin carboxyl-terminal hydrolase 16
- ubiquitin specific peptidase 16
- ubiquitin thioesterase 16
- Ubiquitin thiolesterase 16
- Ubiquitin-processing protease UBP-M
- ubiquitin-specific processing protease 16
- Ubiquitin-specific-processing protease 16
- Ubp-M
- UBP-M
|
Research Areas for USP16
Find related products by research area and learn more about each of the different research areas below.
Cell Cycle and Replication