UPF3A Products

Antibodies
UPF3A Antibody
UPF3A Antibody
NBP1-83136
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
UPF3A Antibody (2E2)
UPF3A Antibody (2E2)
H00065110-M06
Species: Hu
Applications: WB, ELISA, IHC, IHC-P
Host: Mouse Monoclonal
UPF3A Antibody
UPF3A Antibody
H00065110-B01P
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Polyclonal
Lysates
UPF3A Overexpression Lysate ( ...
UPF3A Overexpression Lysate (Denat...
H00065110-T01
Species: Hu
Applications: WB
Proteins
UPF3A Partial Recombinant Pro ...
UPF3A Partial Recombinant Protein
H00065110-Q01
Species: Hu
Applications: WB, ELISA, PA
UPF3A Partial Recombinant Pro ...
UPF3A Partial Recombinant Protein
H00065110-Q02
Species: Hu
Applications: WB, ELISA, PA
UPF3A Recombinant Protein Ant ...
UPF3A Recombinant Protein Antigen
NBP1-83136PEP
Species: Hu
Applications: AC
RNAi
UPF3A RNAi
UPF3A RNAi
H00065110-R01
Species: Hu
UPF3A RNAi
UPF3A RNAi
H00065110-R02
Species: Hu

Description

UPF3A encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. The encoded protein is one of two functional homologs to yeast Upf3p. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. It forms with Y14 a complex that binds specifically 20 nt upstream of exon-exon junctions. This gene is located on the long arm of chromosome 13. Two splice variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 65110
Alternate Names
  • regulator of nonsense transcripts 3A
  • HUPF3A
  • UPF3hUpf3
  • RENT3AUp-frameshift suppressor 3 homolog A
  • Nonsense mRNA reducing factor 3A
  • UPF3 regulator of nonsense transcripts homolog A (yeast)

Diseases related to UPF3A

Discover more about diseases related to UPF3A.

Impacted Tooth
Genetic Diseases, Inborn

Pathways for UPF3A

View related products by pathway and learn more about each of the pathways below.

Translation
Rna Surveillance
Reverse Transcription
Translational Termination
Neurogenesis
Nuclear Export

PTMs for UPF3A

Learn more about PTMs related to UPF3A.

Phosphorylation

Bioinformatics Tool for UPF3A

Discover related pathways, diseases and genes to UPF3A. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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