UEV2 Products

Antibodies
UEV2 Antibody
UEV2 Antibody
NB100-56360
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
UEV2 Antibody
UEV2 Antibody
NBP2-20800
Species: Hu, Mu, Bovine, Canine, Monkey
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
UEV2 Antibody
UEV2 Antibody
NB100-1026
Species: Hu
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
Lysates
UEV2 Overexpression Lysate (D ...
UEV2 Overexpression Lysate (Denatu...
H00007336-T01
Species: Hu
Applications: WB
UEV2 Overexpression Lysate (N ...
UEV2 Overexpression Lysate (Native)
NBL1-17548
Applications: WB
Proteins
UEV2 Recombinant Protein
UEV2 Recombinant Protein
NBP1-45295
Species: Hu
Applications: PAGE
RNAi
UEV2 RNAi
UEV2 RNAi
H00007336-R01
Species: Hu

Description

The differentiation and activation of monocytes (MO) and monocytic cells is modulated by Vitamin D3. Recently, using mRNA Differential Display technology, Fritsche J, et al have identified a gene which is induced in freshly isolated human blood MO that are cultured for 4 hours with Vitamin D3. This cDNA encodes a putative 16.5 kD protein. The product of this gene has structural homology with yeast MMS2P and human CROC-1, which defines a structurally and functionally conserved UBC-like protein family. This protein was called UEV2. The yeast UEV protein is required together with UBC13 for RAD6/RAD18-dependent postreplicative DNA repair in yeast. These proteins also play a central role in the assembly of K63-linked polyubiquitin chains UEV/UBC complexes have been implicated in the assembly of Lys63-linked polyubiquitin chains that act as a novel signal in postreplicative DNA repair and IkBa kinase activation. Recent crystal structure analysis provides direct evidence that the UEV2 heterodimer is necessary for DNA repair.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 7336
Alternate Names
  • methyl methanesulfonate sensitive 2, S. cerevisiae, homolog of
  • EDAF-1
  • enterocyte differentiation-associated factor EDAF-1
  • Vitamin D3-inducible protein
  • enterocyte differentiation promoting factor
  • Enterocyte differentiation-promoting factor 1
  • EDPF1
  • Enterocyte differentiation-associated factor 1
  • DDVIT1
  • UEV-2
  • 25-dihydroxyvitamin D3-inducible
  • 1 alpha
  • DDVit-1
  • MMS2MMS2 homolog
  • EDPF-1DDVit 1
  • UEV2
  • ubiquitin-conjugating enzyme E2 variant 2

Research Areas for UEV2

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
Core ESC-Like Genes
Stem Cell Markers

PTMs for UEV2

Learn more about PTMs related to UEV2.

Ubiquitination
Reduction

Bioinformatics Tool for UEV2

Discover related pathways, diseases and genes to UEV2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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