UBR4 Products

Antibodies
UBR4 Antibody
UBR4 Antibody
NBP1-28730
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
UBR4 Antibody
UBR4 Antibody
NBP1-28724
Species: Hu
Applications: WB, IHC, IHC-P, IP (-)
Host: Rabbit Polyclonal
UBR4 Antibody (2D12)
UBR4 Antibody (2D12)
H00023352-M01
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
Proteins
Recombinant Human UBR4 Protei ...
Recombinant Human UBR4 Protein
H00023352-Q01
Species: Hu
Applications: WB, ELISA, PA
UBR4 Recombinant Protein Anti ...
UBR4 Recombinant Protein Antigen
NBP1-83003PEP
Species: Hu
Applications: AC
RNAi
UBR4 RNAi
UBR4 RNAi
H00023352-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

p600 is an E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. It recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, p600 forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Additionally p600 regulates integrin-mediated signaling and may play a role in activation of FAK in response to cell-matrix interactions.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 23352
Alternate Names
  • EC 6.3.2
  • N-recognin-4
  • EC 6.3.2.-
  • Zinc finger UBR1-type protein 1
  • 600 kDa retinoblastoma protein-associated factor
  • Retinoblastoma-associated factor of 600 kDa
  • ZUBR1retinoblastoma-associated factor 600-like protein
  • KIAA0462E3 ubiquitin-protein ligase UBR4
  • RBAF600FLJ41863
  • KIAA1307zinc finger, UBR1 type 1
  • p600
  • ubiquitin protein ligase E3 component n-recognin 4

Pathways for UBR4

View related products by pathway and learn more about each of the pathways below.

Proteolysis
Rna Interference

PTMs for UBR4

Learn more about PTMs related to UBR4.

Reduction
Ubiquitination

Bioinformatics Tool for UBR4

Discover related pathways, diseases and genes to UBR4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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