UBE2E3 Products

Description

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse and rat counterparts, which indicates that this enzyme is highly conserved in eukaryotes. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Bioinformatics

Product By Gene ID	10477
Alternate Names	E2-23K EC 6.3.2.19 UBCE4 UbcH9 UBCH9ubiquitin-conjugating enzyme E2E 3 (homologous to yeast UBC4/5) UbcM2 UBE2E3 Ubiquitin carrier protein E3 ubiquitin-conjugating enzyme E2 E3 Ubiquitin-conjugating enzyme E2-23 kDa ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast) Ubiquitin-protein ligase E3

Research Areas for UBE2E3

Find related products by research area and learn more about each of the different research areas below.

DNA replication, Transcription, Translation and Splicing