UbcH7/UBE2L3 Products

Description

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Bioinformatics

Entrez	22195 Mouse 7332 Human
Uniprot	AAH53368 Human NM_003347 Human NP_003338 Human NP_005330. Human P68036 Human UBC7_HUMAN Human
Product By Gene ID	7332
Alternate Names	E2-F1 EC 6.3.2.19 L-UBC UBCE7 UbcH7 UBCH7UbcM4 Ubiquitin carrier protein L3 ubiquitin-conjugating enzyme E2 L3 Ubiquitin-conjugating enzyme E2-F1 ubiquitin-conjugating enzyme E2L 3 ubiquitin-conjugating enzyme UBCH7 Ubiquitin-protein ligase L3

Research Areas for UbcH7/UBE2L3

Find related products by research area and learn more about each of the different research areas below.

Cancer
DNA Repair
Tumor Suppressors