TSTA3 Products

Description

Tissue specific transplantation antigen P35B is a NADP(H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in this gene may cause leukocyte adhesion deficiency, type II.

Bioinformatics

Entrez	7264 Human
Uniprot	NM_003313 Human NP_003304 Human NP_003304.1 Human Q13630 Human
Product By Gene ID	7264
Alternate Names	EC 1.1.1.271 FX GDP-4-keto-6-deoxy-D-mannose epimerase-reductase GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase GDP-L-fucose synthase P35B Protein FX Red cell NADP(H)-binding protein SDR4E13-5 epimerase/4-reductase short chain dehydrogenase/reductase family 4E, member 1 Short-chain dehydrogenase/reductase family 4E member 1 tissue specific transplantation antigen 3 tissue specific transplantation antigen P35B Tissue-specific transplantation antigen-3