TSC22/TSC22D1 Products

Antibodies
TSC22/TSC22D1 Antibody (4H8)
TSC22/TSC22D1 Antibody (4H8)
Species: Hu
Applications: WB, Flow, IHC
Host: Mouse monoclonal
TSC22/TSC22D1 Antibody
TSC22/TSC22D1 Antibody
NBP2-24628
Species: Hu, Mu, Rt, Ca
Applications: WB
Host: Rabbit Polyclonal
TSC22/TSC22D1 Antibody [Uncon ...
TSC22/TSC22D1 Antibody [Unconjugated]
AF3779
Species: Mu, Rt
Applications: WB
Host: Goat Polyclonal
Antibody Pairs
TSC22/TSC22D1 Antibody Pair
TSC22/TSC22D1 Antibody Pair
H00008848-PW1
Species: Hu
Applications: WB, IP
Lysates
TSC22/TSC22D1 Overexpression ...
TSC22/TSC22D1 Overexpression Lysat...
NBL1-17351
Applications: WB
TSC22/TSC22D1 Overexpression ...
TSC22/TSC22D1 Overexpression Lysat...
H00008848-T01
Applications: WB
Proteins
TSC22/TSC22D1 Recombinant Pro ...
TSC22/TSC22D1 Recombinant Protein
H00008848-P01
Species: Hu
Applications: WB, ELISA, PA
TSC22/TSC22D1 Recombinant Pro ...
TSC22/TSC22D1 Recombinant Protein
H00008848-P02
Species: Hu
Applications: WB, ELISA, PA
RNAi
TSC22/TSC22D1 RNAi
TSC22/TSC22D1 RNAi
H00008848-R01
Species: Hu
TSC22/TSC22D1 RNAi
TSC22/TSC22D1 RNAi
H00008848-R02
Species: Hu

Description

Transforming growth factor-beta-stimulated clone-22 (TSC-22) acts as a transcriptionalregulator to modulate cell growth and differentiation and cell death. TSC-22 contains a leucine zipper domain as well as a nuclear export signal, resulting in cytoplasmic localization in living cells. However, concomitant with the induction of apoptosis, TSC-22 translocates from the cytoplasm to the nucleus and shows transcriptional regulatory activity. TSC-22 acts as a major downstream component in the TGF-beta pathway, and also the PPARgamma signalling pathway. The association of these two pathways with tumor suppression, and the significant downregulation of TSC-22 mRNA in various cancer types, such as brain and salivary gland tumors, imply an antiproliferative role for TSC-22.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 8848
Alternate Names
  • TGFB1I4
  • KIAA1994
  • Transforming growth factor beta-1-induced transcript 4 protein
  • TSC22 domain family protein 1
  • Regulatory protein TSC-22
  • TSC22 domain family 1
  • Cerebral protein 2
  • transforming growth factor beta-stimulated protein TSC-22
  • transforming growth factor beta 1 induced transcript 4
  • RP11-269C23.2
  • MGC17597
  • TSC22DKFZp686O19206
  • TGFB-stimulated clone 22 homolog
  • TSC22 domain family, member 1

Research Areas for TSC22/TSC22D1

Find related products by research area and learn more about each of the different research areas below.

Cancer

PTMs for TSC22/TSC22D1

Learn more about PTMs related to TSC22/TSC22D1.

Phosphorylation
Acetylation
Ribosylation

Bioinformatics Tool for TSC22/TSC22D1

Discover related pathways, diseases and genes to TSC22/TSC22D1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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