TRPC6 Products

Antibodies
TRPC6 Antibody
TRPC6 Antibody
NBP1-00142
Species: Hu, Mu
Applications: WB, IP, PEP-ELISA
Host: Goat Polyclonal
TRPC6 Antibody
TRPC6 Antibody
NBP1-77260
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IF
Host: Rabbit Polyclonal
TRPC6 Antibody
TRPC6 Antibody
NBP1-77261
Species: Hu, Mu
Applications: WB, ELISA, IHC, IHC-P, IF
Host: Rabbit Polyclonal
Proteins
Recombinant Human TRPC6 Prote ...
Recombinant Human TRPC6 Protein
H00007225-Q01
Species: Hu
Applications: WB, ELISA, PA
TRPC6 Peptide
TRPC6 Peptide
NBP1-77260PEP
Species: Hu
Applications: AC
TRPC6 Peptide
TRPC6 Peptide
NBP1-77261PEP
Species: Hu
Applications: AC
RNAi
TRPC6 RNAi
TRPC6 RNAi
H00007225-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

The protein encoded by the TRPC6 gene creates receptor-activated cation permeant calcium channels in the cell membrane. Isoform 1 is 931 amino acids in length and is approximately 106 kDa, while isoform 2 is 815 amino acids in lenth at around 93 kDA. Isoform 3 is 876 amino acids long and is just over 100 kDA. Focal segmental glomerulosclerosis 2 (FSGS2) is caused by deficits in the TRPC6 gene. This gene has been linked to diseases such as cystic fibrosis, gigantism, hypertension, kidney disease, glomerulosclerosis, pyloric stenosis, diencephalic neoplasm, premature ovarian failure, and hepatopulmonary syndrome. The TRPC6 gene interacts with MX1, ORAI1, NPHS1, NPHS2, and FYN genes in pathways that monitor sodium as well as calcium channels, EPO signaling pathway, G alpha (q) signaling events, signal transduction, and platelet homeostasis.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Rat
Product By Gene ID 7225
Alternate Names
  • FSGS2
  • TrpC6
  • TRP-6
  • short transient receptor potential channel 6
  • Transient receptor protein 6
  • TRP6FLJ14863
  • FLJ11098
  • transient receptor potential cation channel, subfamily C, member 6

Research Areas for TRPC6

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction

Bioinformatics Tool for TRPC6

Discover related pathways, diseases and genes to TRPC6. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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