TRIM5 alpha Products

Antibodies
TRIM5 alpha Antibody
TRIM5 alpha Antibody
NBP1-76601
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
TRIM5 alpha Antibody (3B11H2) ...
TRIM5 alpha Antibody (3B11H2)
NB100-2192
Species: Hu
Applications: WB, ELISA, IHC, IHC-Fr, IHC-P
Host: Mouse Monoclonal
TRIM5 alpha Antibody
TRIM5 alpha Antibody
NBP1-76600
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Rabbit Polyclonal
Proteins
TRIM5 alpha Peptide
TRIM5 alpha Peptide
NBP1-76600PEP
Species: Pm
Applications: AC

Description

TRIM5-alpha is a protein that is found in the cells of many mammals and fends of various retrovirus infections. It protects monkeys from infection with HIV-1, and humans from infection with some other viruses. If a retrovirus has entered a cell, it needs to shed its capsid in order to reversely transcribe its genes, so that they can be expressed by the host cell. It is believed that TRIM5 alpha, which is present in the cytoplasm, somehow recognizes the capsid and blocks its shedding, thereby stopping the virus in its tracks. It thus represents an intracellular defense completely separate from the rest of the body's immune system.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 85363
Alternate Names
  • EC 6.3.2
  • EC 6.3.2.-
  • RING finger protein 88
  • tripartite motif-containing protein 5
  • tripartite motif-containing 5
  • tripartite motif protein TRIM5
  • TRIM5alpha
  • RNF88tripartite motif protein TRIM
  • tripartite motif containing 5

Research Areas for TRIM5 alpha

Find related products by research area and learn more about each of the different research areas below.

Immunology
Lipid and Metabolism
Virology, Bacteria and Parasites
Zinc Finger

PTMs for TRIM5 alpha

Learn more about PTMs related to TRIM5 alpha.

Ubiquitination
Sumoylation
Cleavage

Bioinformatics Tool for TRIM5 alpha

Discover related pathways, diseases and genes to TRIM5 alpha. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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