WB, ELISA, ICC/IF, IHC, IHC-PHost:
Applications: WB, ELISA, IHC, IHC-P
Host: Rabbit Polyclonal
TRIM5-alpha is a protein that is found in the cells of many mammals and fends of various retrovirus infections. It protects monkeys from infection with HIV-1, and humans from infection with some other viruses. If a retrovirus has entered a cell, it needs to shed its capsid in order to reversely transcribe its genes, so that they can be expressed by the host cell. It is believed that TRIM5 alpha, which is present in the cytoplasm, somehow recognizes the capsid and blocks its shedding, thereby stopping the virus in its tracks. It thus represents an intracellular defense completely separate from the rest of the body's immune system.
|Product By Gene ID
- EC 6.3.2
- EC 6.3.2.-
- RING finger protein 88
- tripartite motif-containing protein 5
- tripartite motif-containing 5
- tripartite motif protein TRIM5
- RNF88tripartite motif protein TRIM
- tripartite motif containing 5
Bioinformatics Tool for TRIM5 alpha
Discover related pathways, diseases and genes to TRIM5 alpha. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.