Trim22 Products

Description

Trim22 is encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. [provided by RefSeq]

Bioinformatics

Entrez	10346 Human
Uniprot	NP_006065 Human NP_006065.2 Human NM_006074 Human Q8IYM9 Human
Product By Gene ID	10346
Alternate Names	EC 6.3.2 RING finger protein 94 Staf-50 50 kDa-stimulated trans-acting factor EC 6.3.2.- Tripartite motif-containing protein 22 tripartite motif protein TRIM22 tripartite motif-containing 22 tripartite binding motif 22 GPSTAF50 RNF94stimulated trans-acting factor (50 kDa) STAF50staf-50 E3 ubiquitin-protein ligase TRIM22 tripartite motif containing 22

Diseases related to Trim22

Discover more about diseases related to Trim22.

Hiv Infections
Neoplasms
Immunologic Deficiency Syndromes
Malignant Neoplasms
Hepatitis
Leukemia
Hepatitis B
Cell Transformation, Neoplastic
Retroviridae Infections
Autoimmune Diseases
Nephroblastoma
Rubella
Leukoencephalopathy, Progressive Multifocal
Infective Disorder
Virus Diseases
Autoimmune Reaction
Autoimmunity
Neoplasm Metastasis

Pathways for Trim22

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Localization
Pathogenesis
Viral Replication
Cell Cycle
Cell Activation
Cell Proliferation
Cell Cycle Phase
T Cell Activation
Cellular Process
Immune Response
Adaptive Immune Response
Donor Selection
Tropism
Cell Cycle Arrest
Reverse Transcription
Viral Transcription
Translation
Cell Growth
T Cell Costimulation
Chromatin Remodeling

Research Areas for Trim22

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Zinc Finger

PTMs for Trim22

Learn more about PTMs related to Trim22.

Ubiquitination

Bioinformatics Tool for Trim22

Discover related pathways, diseases and genes to Trim22. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.