Hu, Mouse, RatApplications:
ICC/IF, IHC, IHC-PHost:
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
The TRIAD3 gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known.
|Product By Gene ID
- Triad domain-containing protein 3
- EC 6.3.2.-
- UBCE7IP1ubiquitin conjugating enzyme 7 interacting protein 1
- ZINE3 ubiquitin-protein ligase RNF216
- TRIAD3Zinc finger protein inhibiting NF-kappa-B
- ring finger protein 216Ubiquitin-conjugating enzyme 7-interacting protein 1
Bioinformatics Tool for TRIAD3
Discover related pathways, diseases and genes to TRIAD3. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.