Species: Hu
Applications: WB, IHC, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: IHC, IP, WB (-)
Host: Rabbit Polyclonal
Species: Hu, Rt
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
The transcriptional regulating protein of 132 kDa (TReP-132/TRERF1) was identified as a transcription factor that interacts with and activates the promoter of the CYP11A1 gene, a gene that encodes cytochrome P450 side chain cleavage (P450scc) and catalyzes the first step in steroidgenesis. TRep-132 can function as a nuclear receptor co-activator and has been shown to interact with Sp1 and the progesterone receptor (PR) to suppress growth via activation of the gene promoters of the cyclin-dependent kinase inhibitors, p21 and p27.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
55809 |
| Alternate Names |
- BCAR2
- Breast cancer estrogen resistance 2RAPAHSA277276
- dJ139D8.5
- FLJ21198
- rapa-1
- rapa-2
- RP1-139D8.5
- transcriptional regulating factor 1
- transcriptional regulating protein 132
- transcriptional-regulating factor 1
- Transcriptional-regulating protein 132
- TREP132
- TReP-132
- Zinc finger protein rapa
- Zinc finger transcription factor TReP-132
|
