Translin Products

Antibodies
Translin Antibody
Translin Antibody
NBP2-31779
Species: Hu, Mouse
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Translin Antibody
Translin Antibody
NBP1-76581
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC
Host: Rabbit Polyclonal
Proteins
Translin Recombinant Protein ...
Translin Recombinant Protein Antigen
NBP2-31779PEP
Species: Hu
Applications: AC
Translin Recombinant Protein
Translin Recombinant Protein
NBP1-49449
Species: Hu
Applications: PAGE
Translin Peptide
Translin Peptide
NBP1-76581PEP
Species: Hu
Applications: AC
RNAi
Translin RNAi
Translin RNAi
H00007247-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Translin, also designated testis brain RNA-binding protein (TB-RBP), is a single-stranded DNA- and RNA-binding protein that binds to the 3' UTR regions (Y and H elements) of stored mRNAs, which suppresses their in vitro translation. The human translin gene maps to chromosome 2q21.1 and encodes a 26 kDa protein that has been highly conserved throughout evolution. Translin forms a ring-shaped structure, which is responsible for DNA binding, and also contains a leucine zipper motif, which is thought to enable translin to form dimers. Translin exports specific mRNAs out of the nucleus, supported by its localization in both the nuclei and cytoplasm of neurons, and regulates their translation. Association with Trax (translin-associated factor X), inhibits the binding of translin to RNA, but enhances its binding to single stranded DNA sequences. Breakpoints in the TLS/FUS and CHOP loci contain consensus recognition motifs of translin, which associates with chromosomal translocations in liposarcomas.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 7247
Alternate Names
  • recombination hotspot-binding protein
  • recombination hotspot associated factor
  • TRSLN
  • TBRBP
  • REHF-1
  • RCHF1
  • BCLF-1
  • translin

PTMs for Translin

Learn more about PTMs related to Translin.

Cleavage
Phosphorylation
Sumoylation
Reduction
Oxidation
Methylation
Ubiquitination

Bioinformatics Tool for Translin

Discover related pathways, diseases and genes to Translin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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