TMPRSS11E Products

Antibodies
TMPRSS11E Antibody
TMPRSS11E Antibody
45460002
Species: Hu
Applications: WB, ELISA
Host: Rabbit Polyclonal
TMPRSS11E Antibody
TMPRSS11E Antibody
NBP2-48995
Species: Hu
Applications: IHC
Host: Rabbit Polyclonal
Lysates
TMPRSS11E Overexpression Lysa ...
TMPRSS11E Overexpression Lysate (N...
NBP2-07384
Applications: WB
Proteins
TMPRSS11E Recombinant Protein ...
TMPRSS11E Recombinant Protein Antigen
NBP2-48995PEP
Species: Hu
Applications: AC
Recombinant Human TMPRSS11E P ...
Recombinant Human TMPRSS11E Protein
H00028983-G01-10ug
Species: Hu

Description

TMPRSS11E is a member of a larger family of membrane attached serine proteases, a poorly defined group that includes TMPRSS11A, B, C, D, E, F, Hepsin, Corin, Matriptase 1, 2 and 3. The highest degree of identity is with TMPRSS11A, which shares 43% identity at the amino acid level. TMPRSS11E has a domain structure of an aminoterminal cytoplasmic domain, followed by a transmembrane domain, a SEA domain (Sea urchin sperm protein, Enterokinase, Agrin), a short spacer, then the trypsin like serine protease domain. The SEA domain is thought to play a role in carbohydrate binding in the analogous protein sequences where it is found, but the role in TMPRSS11E is unclear. The cleavage of the Arg191 Ile192 bond liberates the catalytic domain. TMPRSS11E has been shown to cleave fibronectin, gelatin, casein and pro uPA in vitro, and to form complexes with serpinA5 and serpinE1.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 28983
Alternate Names
  • DESC1
  • MGC141972
  • serine 11E2
  • transmembrane protease serine 11E
  • TMPRSS11E2
  • serine protease DESC1
  • FLJ94490
  • FLJ75331
  • MGC141974
  • UNQ742/PRO1461
  • transmembrane protease serine 11E2
  • transmembrane protease, serine 11E

Bioinformatics Tool for TMPRSS11E

Discover related pathways, diseases and genes to TMPRSS11E. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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