TLR3 Products

Antibodies
TLR3 Antibody
TLR3 Antibody
NB100-56571
Species: Hu, Mu, Po
Applications: WB, Flow, IHC, IHC-Fr, IHC-P
Host: Rabbit Polyclonal
Conjugate Catalog # Availability Size Price
TLR3 Antibody
TLR3 Antibody
NBP2-24565
Species: Hu, Mu, Rt, Av, Bv, Ch, Op, Pm
Applications: WB, Flow, IHC-P
Host: Rabbit Polyclonal
Antibody Packs
Lysates
TLR3 Overexpression Lysate (N ...
TLR3 Overexpression Lysate (Native)
NBP2-08025
Applications: WB
Proteins
Human TLR3 Biologically Activ ...
Human TLR3 Biologically Active Pro...
NBP2-36592
Species: Hu
Applications: Func, PAGE
Human TLR3 Biologically Activ ...
Human TLR3 Biologically Active Pro...
NBP2-36506
Species: Hu
Applications: PAGE
TLR3 Partial Recombinant Prot ...
TLR3 Partial Recombinant Protein
H00007098-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
TLR3 RNAi
TLR3 RNAi
H00007098-R02
Species: Hu
Reporter Cell Lines
Human TLR3 NF-kB/SEAP - (SEAP ...
Human TLR3 NF-kB/SEAP - (SEAPorter...
NBP2-26275
Applications: Flow, LA
Host: HEK293
Human TLR3 Stable Cell Line
Human TLR3 Stable Cell Line
NBP2-26267
Host: HEK293

Description

The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1) and could constitute an important and unrecognized component of innate immunity in humans. The TRL family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition (2). TLRs characterized so far activate the MyD88/interleukin-1 receptor-associated kinase (IRAK) signaling pathway. Ten human homologs of TLRs (TLR1-10) have been described (3). mTLR3 cDNA codes for a protein with approximate molecular weight of 100 kDa. TLR3 has a restricted expression pattern being expressed in dendritic cells (DC) (4-5). TLR3 mRNA expression was detected by in situ hybridization in DC and lymph nodes. The expression of TLR3 in a single cell type may indicate a specific role for this molecule in a restricted setting.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 7098
Alternate Names
  • CD283 antigen
  • CD283
  • toll-like receptor 3

Research Areas for TLR3

Find related products by research area and learn more about each of the different research areas below.

Cytokine Research
Immune System Diseases
Immunology
Innate Immunity
Signal Transduction
Toll-Like Receptors

Bioinformatics Tool for TLR3

Discover related pathways, diseases and genes to TLR3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related TLR3 Blog Posts

Check out the latest blog posts on TLR3.
TRIF/TICAM1 and mitochondrial dynamics in the innate immune response
TRIF, also known as toll like receptor adaptor molecule 1 or TICAM1, is known for its role in invading foreign pathogens as part of our innate immune response. TRIF/TICAM1 is a TIR-domain adaptor protein (toll/interleukin-1 receptor) that interacts...    Read more.
The role of TLR4 in breast cancer
Toll like receptors (TLRs) are highly conserved proteins that are first known for their role in pathogen recognition and immune response activation.  In order to elicit the necessary immune response in reaction to a foreign pathogen, TLRs trigger cy...    Read more.
Read more TLR3 related blogs.