TIP60 Products

Antibodies
TIP60 Antibody
TIP60 Antibody
NBP2-24613
Species: Hu
Applications: WB, Simple Western, IHC-P
Host: Rabbit Polyclonal
TIP60 Antibody
TIP60 Antibody
NBP2-20647
Species: Hu, Mu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
TIP60 Antibody
TIP60 Antibody
NBP1-85482
Species: Hu, Mouse, Rat
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Antibody Pairs
TIP60 Antibody Pair
TIP60 Antibody Pair
H00010524-PW1
Species: Hu
Applications: WB, IP
Lysates
TIP60 Overexpression Lysate ( ...
TIP60 Overexpression Lysate (Denat...
H00010524-T01
Species: Hu
Applications: WB
TIP60 Overexpression Lysate ( ...
TIP60 Overexpression Lysate (Native)
NBL1-12125
Applications: WB
TIP60 Overexpression Lysate ( ...
TIP60 Overexpression Lysate (Native)
NBL1-12126
Applications: WB
Proteins
TIP60 Recombinant Protein
TIP60 Recombinant Protein
H00010524-P01
Species: Hu
Applications: WB, ELISA, PA
TIP60 Partial Recombinant Pro ...
TIP60 Partial Recombinant Protein
H00010524-Q01
Species: Hu
Applications: WB, ELISA, PA
TIP60 Recombinant Protein Ant ...
TIP60 Recombinant Protein Antigen
NBP1-85482PEP
Species: Hu
Applications: AC
RNAi
TIP60 RNAi
TIP60 RNAi
H00010524-R03
Species: Hu
Applications: RNAi, RNAi SP
TIP60 RNAi
TIP60 RNAi
H00010524-R01
Species: Hu
Applications: RNAi, RNAi SP
TIP60 RNAi
TIP60 RNAi
H00010524-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

HTATIP (HIV-1 Tat interacting protein TIP60, about 60kDa) belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. In addition to the growing number of post-translational histone modifications regulating chromatin structure, cells can also exchange canonical histones with variant histones that can directly or indirectly modulate chromatin structure. There are five major variants of histone H2A: canonical H2A (most abundant), H2A.X, MacroH2A, H2ABbd and H2A.Z. Histone H2A.Z, the most conserved variant across species, functions as both a positive and negative regulator of transcription and is important for chromosome stability. Several homologous protein complexes, such as SWR-C, TIP60 and SRCAP (mammals), have been shown to catalyze the ATP-dependent exchange of H2A.Z for H2A in the nucleosome. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 10524
Alternate Names
  • HIV-1 Tat interactive protein
  • Lysine acetyltransferase 5
  • Tip60
  • Histone acetyltransferase HTATIP
  • Tat interacting protein, 60kDa
  • HIV-1 Tat interactive protein, 60kDa
  • K-acetyltransferase 5
  • cPLA2
  • histone acetyltransferase KAT5
  • HTATIP1
  • HTATIPcPLA2 interacting protein
  • PLIPTIP
  • ESA1EC 2.3.1.48
  • TIP60cPLA(2)-interacting protein
  • K(lysine) acetyltransferase 5,60 kDa Tat-interactive protein

Research Areas for TIP60

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
DNA Repair

Bioinformatics Tool for TIP60

Discover related pathways, diseases and genes to TIP60. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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