Applications: WB, Simple Western
Host: Mouse Monoclonal
Host: Goat Polyclonal
TFR2 is a gene that codes for a protein with three isoforms, with lengths of 801, 630, and 774 amino acids and weights of approximately 89, 70, and 86 kDa respectively. TFR2 helps in the cellular uptake of transferrin-bound iron as well as iron metabolism, erythrocyte differentiation, and hepatocyte function. Current studies are being done on several diseases and disorders related to this gene including porphyria cutanea tarda, iron overload, beta thalassemia, liver cirrhosis, hepatitis C, fatty liver disease, leukemia, lymphoma, liver disease, and cystic fibrosis. TRF2 has also been shown to have interactions with HFE, TF, UBC, and SOCS3 in pathways such as the AMPK enzyme complex and iron metabolism in the placenta pathways.
|Product By Gene ID
- HFE3transferrin receptor protein 2
- transferrin receptor 2
Bioinformatics Tool for TfR2
Discover related pathways, diseases and genes to TfR2. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.