Species: Hu, Mu
Applications: WB, IHC, IP
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, Flow, Mycoplasma
Host: Rabbit Monoclonal
Species: Hu
Applications: PAGE
Description
TCEB2 encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Bioinformatics
| Product By Gene ID |
6923 |
| Alternate Names |
- 18-kD subunit
- EloB
- Elongin 18 kDa subunit
- elongin-B
- RNA polymerase II transcription factor SIII p18 subunit
- RNA polymerase II transcription factor SIII subunit B
- SIII p18
- transcription elongation factor B (SIII), polypeptide 2 (18kD, elongin B)
- transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
- transcription elongation factor B polypeptide 2
|
Research Areas for TCEB2
Find related products by research area and learn more about each of the different research areas below.
Cell Biology
