TAK1 Products

Antibodies
TAK1 Antibody
TAK1 Antibody
NB100-56363
Species: Hu, Mu
Applications: WB
Host: Rabbit Polyclonal
TAK1 Antibody (2E10.)
TAK1 Antibody (2E10.)
H00006885-M02
Species: Hu
Applications: WB, ELISA, RNAi
Host: Mouse Monoclonal
TAK1 Antibody (491840)
TAK1 Antibody (491840)
MAB5307
Species: Hu
Applications: WB
Host: Mouse Monoclonal
Antibody Pairs
TAK1 Antibody Pair
TAK1 Antibody Pair
H00006885-PW1
Species: Hu
Applications: WB, IP
Lysates
TAK1 Overexpression Lysate (N ...
TAK1 Overexpression Lysate (Native)
NBP2-10876
Applications: WB
TAK1 Overexpression Lysate (D ...
TAK1 Overexpression Lysate (Denatu...
H00006885-T01
Species: Hu
Applications: WB
Proteins
Recombinant Human TAK1 Protei ...
Recombinant Human TAK1 Protein
H00006885-P01
Species: Hu
Applications: WB, ELISA, PA, PAGE, KA
Recombinant Human TAK1 Protei ...
Recombinant Human TAK1 Protein
H00006885-Q01
Species: Hu
Applications: WB, ELISA, PA
TAK1 Recombinant Protein Anti ...
TAK1 Recombinant Protein Antigen
NBP1-87819PEP
Species: Hu
Applications: AC
RNAi
TAK1 RNAi
TAK1 RNAi
H00006885-R01V
Species: Hu
Applications: WB, RNAi, RNAi SP
TAK1 RNAi
TAK1 RNAi
H00006885-R02V
Species: Hu
Applications: WB, RNAi, RNAi SP
TAK1 RNAi
TAK1 RNAi
H00006885-R12
Species: Hu
Applications: RNAi, RNAi SP

Description

TAK1 (or MAP3K7) was shown to participate in regulation of transcription by transforming growth factor beta (TGF beta). TAK1 is stimulated in response to TGF beta and bone morphogenetic protein. These results suggest that TAK1 functions as a mediator in the signaling pathway of TGF beta superfamily members. TAB1 and TAB2 are TAK1 binding proteins that may function as activators of the TAK1 (TGF b activated kinase 1) MAPKKK in TGF b signal transduction. TAB1 induced TAK1 activation promoted the dissociation of active forms of IKKa and IKK b from active TAK1, whereas the IKK mutants remained to interact with active TAK1. TNF a activated endogenous TAK1, and the kinase negative TAK1 acted as a dominant negative inhibitor against TNF a induced NFkB activation. TAK1 was suggested to act as a regulatory kinase of IKKs.

Bioinformatics

Entrez Human
Mouse
Mouse
Rat
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 6885
Alternate Names
  • TAK1/MAP3K7
  • TGF-beta-activated kinase 1
  • EC 2.7.11
  • Transforming growth factor-beta-activated kinase 1
  • TGF-beta activated kinase 1
  • MEKK7
  • TAK1TGF1a
  • EC 2.7.11.25
  • mitogen-activated protein kinase kinase kinase 7

Research Areas for TAK1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Immunology
Innate Immunity
Phospho-Specific
Protein Kinase
Signal Transduction
Wnt Signaling Pathway

PTMs for TAK1

Learn more about PTMs related to TAK1.

Phosphorylation
Ubiquitination
Acetylation

Bioinformatics Tool for TAK1

Discover related pathways, diseases and genes to TAK1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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