TAB1 Products

Description

TAB1, TAK1 binding protein, enhances activity of the plasminogen activator inhibitor 1 gene promoter, which is regulated by TGF-beta, and increases the kinase activity of TAK1. TAB1 may function as an activator of the TAK1 MAPKKK in TGF-beta signal transduction (1). Findings suggest that alternative activation pathways contribute to the biological responses of p38alpha to various stimuli. Interaction of p38alpha with TAB1 leads to autophosphorylation and activation of p38alpha (2).

Bioinformatics

Entrez	10454 Human 315139 Rat 66513 Mouse
Uniprot	AAH50554 Human AAH50554.1 Human NP_006107 Human NP_006107.1 Human NP_705717 Human NP_705717.1 Human Q15750 Human Q8IZW2 Human
Product By Gene ID	10454
Alternate Names	MAP3K7IP13'-Tab1 MGC57664 mitogen-activated protein kinase kinase kinase 7 interacting protein 1 Mitogen-activated protein kinase kinase kinase 7-interacting protein 1 TAK1-binding protein 1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 TGF-beta-activated kinase 1-binding protein 1 transforming growth factor beta-activated kinase-binding protein 1

Research Areas for TAB1

Find related products by research area and learn more about each of the different research areas below.

Immunology
Innate Immunity
Phospho-Specific