ST6 Gal Sialyltransferase 1/ST6GAL1/CD75 Products

Description

CD75 is encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP sialic acid to galactose-containing substrates. The encoded protein, which is normally found in the Golgi apparatus but which can be proteolytically processed to a soluble form, is involved in the generation of the cell surface carbohydrate determinants and differentiation antigens HB6, CDw75, and CD76. This protein is a member of glycosyltransferase family 29. Three transcript variants encoding two different isoforms have been found for this gene. This antibody recognizes the CD75 cell surface antigen, an alpha 2,6 sialyated carbohydrate epitope expressed by mature B cells, especially germinal centre B cells, red blood cells and some epithelial cells.

Bioinformatics

Entrez	6480 Human
Uniprot	NM_173216 Human NM_173217 Human NM_003032 Human P15907 Human NP_775323 Human NP_775324.1 Human
Product By Gene ID	6480
Alternate Names	Sialyltransferase 1 sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase) sialyltransferase 1 (beta-galactoside alpha-2,6-sialyltransferase) EC 2.4.99.1 CMP-N-acetylneuraminate beta-galactosamide alpha-2,6-sialyltransferase ST6Gal I beta-galactoside alpha-2,6-sialyltransferase 1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1 ST6N B-cell antigen CD75 ST6GalI SIAT1Alpha 2,6-ST 1 MGC48859 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1

Diseases related to ST6 Gal Sialyltransferase 1/ST6GAL1/CD75

Discover more about diseases related to ST6 Gal Sialyltransferase 1/ST6GAL1/CD75.

Neoplasms
Malignant Neoplasms
Malignant Paraganglionic Neoplasm
Carcinoma
Neoplasm Metastasis
Lymphoma
B-cell Lymphomas
Cell Transformation, Neoplastic
Malignant Neoplasm Of Stomach
Stomach Neoplasms
Adenocarcinoma
Tumor Progression
Tissue Adhesions
Lymphatic Metastasis
Diabetes Mellitus
Leukemia
Liver Carcinoma
Diffuse Large B-cell Lymphoma
Malignant Tumor Of Colon

Pathways for ST6 Gal Sialyltransferase 1/ST6GAL1/CD75

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Glycosylation
Cell Proliferation
Cell Cycle
Localization
Fucosylation
Macrophage Differentiation
Cell Growth
Angiogenesis
Pathogenesis
Secretion
Transport
Cell Adhesion
Lipoprotein Transport
Immune Response
Cell Maturation
Inflammatory Response
Flight
Cell Motility
Neutrophil Homeostasis
Cell Differentiation

Research Areas for ST6 Gal Sialyltransferase 1/ST6GAL1/CD75

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Golgi Apparatus Markers

PTMs for ST6 Gal Sialyltransferase 1/ST6GAL1/CD75

Learn more about PTMs related to ST6 Gal Sialyltransferase 1/ST6GAL1/CD75.

Glycosylation
Phosphorylation
Cleavage
Amination

Bioinformatics Tool for ST6 Gal Sialyltransferase 1/ST6GAL1/CD75

Discover related pathways, diseases and genes to ST6 Gal Sialyltransferase 1/ST6GAL1/CD75. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.