SSB Products

Human SSB ELISA Kit (Colorime ...
Human SSB ELISA Kit (Colorimetric)
Species: Hu
Applications: ELISA
SSB Overexpression Lysate
SSB Overexpression Lysate
Species: Hu
Applications: WB
Recombinant Human SSB GST (N- ...
Recombinant Human SSB GST (N-Term)...
Species: Hu
Applications: WB, ELISA, PA, AP
Recombinant Human SSB GST (N- ...
Recombinant Human SSB GST (N-Term)...
Species: Hu
Applications: WB, ELISA, PA, AP
SSB Recombinant Protein Antig ...
SSB Recombinant Protein Antigen
Species: Hu
Applications: AC


Members of the suppressor of cytokine signaling (SOCS) family of proteins contain C-terminal regions of homology called the SOCS box, which serves to couple SOCS proteins and their binding partners with the Elongin B and C complex, thereby mediating protein degradation. Several other families of proteins also contain SOCS boxes, but differ from the SOCS proteins in the type of domain they contain upstream of the SOCS box. SSB-2 (SplA/ryanodine (SPRY) receptor domain-containing SOCS box protein 2), also known as GGRCC9 (gene-rich cluster protein C9), SPSB2 or MGC2519, is a cytoplasmic protein belonging to the SPSB family of proteins that contain a central SPRY domain and a C-terminal SOCS box. The SPRY domain is believed to be a protein-protein interaction motif. Members of the SPSB family are capable of interacting with Met (a receptor for hepatocyte growth factors (HGFs)), and SSB-1 is known to promote HGF signaling. SSB-1, SSB-2 and SSB-4 are also able to interact with PAR4 (prostate apoptosis response protein 4). Mutations in the genes encoding SPSB proteins are associated with several human diseases.


Entrez Human
Uniprot Human
Product By Gene ID 6741
Alternate Names
  • La ribonucleoprotein
  • SS-B
  • SS-B/La protein
  • Sjoegren syndrome type B antigen
  • lupus La protein
  • La autoantigen
  • member 3
  • Sjogren syndrome antigen B (autoantigen La)

Research Areas for SSB

Find related products by research area and learn more about each of the different research areas below.

Core ESC-Like Genes
Stem Cell Markers

Bioinformatics Tool for SSB

Discover related pathways, diseases and genes to SSB. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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