SPEN Products

Antibodies
SPEN Antibody
SPEN Antibody
NBP1-82952
Species: Hu, Mu, Rat
Applications: ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
SPEN Antibody
SPEN Antibody
NB100-58798
Species: Hu
Applications: WB, IP
Host: Rabbit Polyclonal
SPEN Antibody
SPEN Antibody
NB100-58799
Species: Hu, Primate, Monkey
Applications: IP
Host: Rabbit Polyclonal
Proteins
SPEN Recombinant Protein Anti ...
SPEN Recombinant Protein Antigen
NBP1-82952PEP
Species: Hu
Applications: AC
RNAi
SPEN RNAi
SPEN RNAi
H00023013-R01
Species: Hu

Description

SPEN encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins. This domain also permits interaction with members of the NuRD complex, a nucleosome remodeling protein complex that contains deacetylase activity. In addition, this repressor contains several RNA recognition motifs that confer binding to a steroid receptor RNA coactivator; this binding can modulate the activity of both liganded and nonliganded steroid receptors.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 23013
Alternate Names
  • SPEN homolog
  • SMART/HDAC1-associated repressor protein
  • SMART/HDAC1 associated repressor protein
  • RBM15C
  • KIAA0929nuclear receptor transcription cofactor
  • SHARPmsx2-interacting protein
  • MINTMsx2 interacting nuclear target (MINT) homolog
  • HIAA0929
  • spen homolog, transcriptional regulator (Drosophila)

PTMs for SPEN

Learn more about PTMs related to SPEN.

Phosphorylation
Methylation
Cleavage

Bioinformatics Tool for SPEN

Discover related pathways, diseases and genes to SPEN. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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