Spectrin beta 1 Products

Description

Spectrin (Sp), the most abundant of the erythrocyte membrane skeleton proteins, helps these cells maintain their characteristic biconcave shape while remaining flexible and elastic. Erythrocyte Sp is a heterodimer composed of a 280 kDa alpha subunit and a 246 kDa beta subunit which associate in a side-to-side, antiparallel configuration to form a 100 nm rod-like structure. Sp in other tissues may be composed of distinct but homologous alpha and beta subunits, sometimes referred to as fodrin. A newly introduced nomenclature designates the Sp subunits of the erythrocyte as alpha-1 and beta-1, and the fodrin subunits as alpha-2 and beta-2. Alternatively spliced forms of each are designated as epsilon-1, epsilon-2, etc. (e.g. beta-1 epsilon-1).

Bioinformatics

Entrez	314251 Rat 6710 Human
Uniprot	P11277 Human
Product By Gene ID	6710
Alternate Names	beta-I spectrin EL3 erythrocyte HS2 HSPTB1 membrane cytoskeletal protein spectrin, beta, erythrocytic SPTB1

Research Areas for Spectrin beta 1

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Cytoskeleton Markers