SOD3/EC-SOD Products

Antibodies
SOD3/EC-SOD Antibody
SOD3/EC-SOD Antibody
AF4817
Species: Mu
Applications: WB
Host: Goat Polyclonal
SOD3/EC-SOD Antibody [Unconju ...
SOD3/EC-SOD Antibody [Unconjugated]
AF3420
Species: Hu
Applications: WB, Simple Western, IHC
Host: Goat Polyclonal
ELISA Kits
SOD3/EC-SOD ELISA Kit
SOD3/EC-SOD ELISA Kit
NBP1-90377
Species: Hu
Applications: ELISA
SOD3/EC-SOD ELISA Kit [HRP]
SOD3/EC-SOD ELISA Kit [HRP]
KA0529
Species: Hu
Lysates
SOD3/EC-SOD Overexpression Ly ...
SOD3/EC-SOD Overexpression Lysate ...
NBL1-16335
Applications: WB
Proteins
SOD3/EC-SOD Partial Recombina ...
SOD3/EC-SOD Partial Recombinant Pr...
H00006649-Q01
Species: Hu
Applications: WB, ELISA, PA
SOD3/EC-SOD Recombinant Prote ...
SOD3/EC-SOD Recombinant Protein An...
NBP2-38493PEP
Species: Hu
Applications: AC
RNAi
SOD3/EC-SOD RNAi
SOD3/EC-SOD RNAi
H00006649-R01
Species: Hu

Description

FUNCTION: Destroys radicals which are normally produced within the cells and which are toxic to biological systems. CATALYTIC ACTIVITY: 2 superoxide + 2 H+ = O2 + H2O2. COFACTOR: Binds 1 copper ion per subunit. COFACTOR: Binds 1 zinc ion per subunit. SUBUNIT: Homotetramer. SUBCELLULAR LOCATION: Secreted protein; extracellular space. Note=99% of EC-SOD is anchored to heparan sulfate proteoglycans in the tissue interstitium, and 1% is located in the vasculature in quilibrium between the plasma and the endothelium. TISSUE SPECIFICITY: Major SOD isoenzyme in extracellular fluids such as plasma, lymph and synovial fluid. POLYMORPHISM: The variant Gly-231 which is found in about 2.2% of individual displays a 10-fold increased plasma EC-SOD content due to reduced heparin-binding affinity and thus the impairment of its binding ability to endothelial cell surface. SIMILARITY: Belongs to the Cu-Zn superoxide dismutase family.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 6649
Alternate Names
  • extracellular superoxide dismutase [Cu-Zn]
  • MGC20077
  • EC-SODEC 1.15.1.1
  • superoxide dismutase 3, extracellular

Bioinformatics Tool for SOD3/EC-SOD

Discover related pathways, diseases and genes to SOD3/EC-SOD. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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