Snail Products

Antibodies
Snail Antibody
Snail Antibody
NBP2-27184
Species: Hu, Mu, Ca, Eq
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Snail Antibody
Snail Antibody
NBP2-27293
Species: Hu
Applications: Simple Western, IHC-P
Host: Rabbit Polyclonal
Snail Antibody [Unconjugated] ...
Snail Antibody [Unconjugated]
AF3639
Species: Hu
Applications: WB, ChIP, ICC, ICFlow
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Antibody Pairs
Snail Antibody Pair
Snail Antibody Pair
H00006615-AP11
Species: Hu
Applications: S-ELISA
Snail Antibody Pair
Snail Antibody Pair
H00006615-AP21
Species: Hu
Applications: S-ELISA
Snail Antibody Pair
Snail Antibody Pair
H00006615-PW2
Species: Hu
Applications: WB, IP
Lysates
Snail Overexpression Lysate ( ...
Snail Overexpression Lysate (Denat...
H00006615-T01
Species: Hu
Applications: WB
Snail Overexpression Lysate ( ...
Snail Overexpression Lysate (Native)
NBL1-16265
Applications: WB
Proteins
Recombinant Human Snail Prote ...
Recombinant Human Snail Protein
NBP2-22814
Species: Hu
Applications: PAGE
RNAi
Snail RNAi
Snail RNAi
H00006615-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

The SNAIL family of developmental regulatory proteins is a group of widely conserved zinc-finger proteins that regulate transcription and include the mammalian proteins SLUG, SNAI 1, the human homolog of Drosophila SNAIL, and Smuc. SNAI 1 and SLUG are expressed in placenta and adult heart, liver and skeletal muscle. SNAI 1, and the corresponding mouse homolog Sna, each contain three classic zinc fingers and one atypical zinc finger, while SLUG contains five zinc finger regions and a transcriptional repression domain at the amino terminus, which enables SLUG to act as a negative regulator of gene expression. SLUG is implicated in the generation and migration of neural crest cells in human embryos and also contributes to limb bud development. In addition, SLUG also constitutes a cellular anti-apoptotic transcription factor that effectively prevents apoptosis in murine pro-B cells deprived of IL-3. The SNAIL-related gene from murine skeletal muscle cells, Smuc, is highly expressed in skeletal muscle and thymus and can, likewise, repress gene transcription. Smuc preferentially associates with CAGGTG and CACCTG E-box motifs (CANNTG) on DNA and involves the five putative DNA-binding zinc finger domains at the C-terminal region of Smuc.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 6615
Alternate Names
  • zinc finger protein SNAI1
  • Protein snail homolog 1
  • snail 1, zinc finger protein
  • Protein sna
  • snail 1 zinc finger protein
  • SNA
  • snail 1 homolog
  • SLUGH2
  • SNAHdJ710H13.1
  • snail 1 (drosophila homolog), zinc finger protein
  • snail homolog 1 (Drosophila)

Research Areas for Snail

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Phospho-Specific

PTMs for Snail

Learn more about PTMs related to Snail.

Phosphorylation
Methylation
Demethylation
Cleavage
Dephosphorylation
Ubiquitination

Bioinformatics Tool for Snail

Discover related pathways, diseases and genes to Snail. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related Snail Blog Posts

Check out the latest blog posts on Snail.
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Epithelial-Mesenchymal Transition (EMT) is the trans-differentiation of stationary epithelial cells into motile mesenchymal cells. During EMT, epithelial cells lose their junctions and apical-basal polarity, reorganize their cytoskeleton, undergo a...    Read more.
Understanding the relationship between HIF-1 alpha, Hypoxia and Epithelial-Mesenchymal Transition
Epithelial-mesenchymal transition (EMT) is a natural process by which epithelial cells lose their polarity and intercellular adhesion, and gain the migratory invasive properties of mesenchymal stem cells that can differentiate into a variety of cel...    Read more.
Read more Snail related blogs.