SMC1 Products

Antibodies
SMC1 Antibody
SMC1 Antibody
NB100-204
Species: Hu, Mu, Xp, Bovine, Canine, Chicken, Equine, Guinea Pig, Primate, Porcine, Rabbit, Rat, Bat, Chinese Hamster, Monkey
Applications: WB, Simple Western, ELISA, ICC/IF, IHC, IHC-P, IP, PLA
Host: Rabbit Polyclonal
Conjugate Catalog # Availability Size Price
SMC1 [p Ser966] Antibody
SMC1 [p Ser966] Antibody
Species: Hu, Mu, Primate, Monkey
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IP, PLA
Host: Rabbit Polyclonal
SMC1 [p Ser957] Antibody
SMC1 [p Ser957] Antibody
Species: Hu, Bovine, Canine, Ferret, Guinea Pig, Primate, Porcine, Rabbit, Monkey
Applications: WB, IP, PLA
Host: Rabbit Polyclonal
Lysates
SMC1 Overexpression Lysate (N ...
SMC1 Overexpression Lysate (Native)
NBL1-16236
Applications: WB
Proteins
SMC1 Partial Recombinant Prot ...
SMC1 Partial Recombinant Protein
H00008243-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
SMC1 RNAi
SMC1 RNAi
H00008243-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

SMC1 is involved in chromosome cohesion during cell cycle and in DNA repair. It is a central component of the cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Involved in DNA repair via its interaction with BRCA1 and its related phosphorylation by ATM, SMC1 works as a downstream effector in the ATM/NBS1 branch of S-phase checkpoint.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Mouse
Product By Gene ID 8243
Alternate Names
  • CDLS2
  • Sb1.8
  • SMC protein 1A
  • structural maintenance of chromosomes protein 1A
  • SMC1L1
  • SMC1 structural maintenance of chromosomes 1-like 1
  • SMC-1A
  • segregation of mitotic chromosomes 1
  • SMC-1-alpha
  • SMCB
  • SMC1 (structural maintenance of chromosomes 1, yeast)-like 1
  • SMC1SMC1alpha
  • SB1.8MGC138332
  • KIAA0178DKFZp686L19178
  • DXS423ESMC1 structural maintenance of chromosomes 1-like 1 (yeast)
  • Smcb
  • structural maintenance of chromosomes 1A

Research Areas for SMC1

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Cycle and Replication
Checkpoint signaling
Chromatin Research
DNA Double Strand Break Repair
DNA Repair
Phospho-Specific

PTMs for SMC1

Learn more about PTMs related to SMC1.

Acetylation
Phosphorylation
Deacetylation
Dephosphorylation
Methylation

Bioinformatics Tool for SMC1

Discover related pathways, diseases and genes to SMC1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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