Smad1 Products

Antibodies
Smad1 Antibody (2E9)
Smad1 Antibody (2E9)
H00004086-M03
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
Smad1 Antibody [Unconjugated] ...
Smad1 Antibody [Unconjugated]
AF2039
Species: Hu
Applications: WB, Simple Western, IHC
Host: Goat Polyclonal
Smad1 Antibody (1D3)
Smad1 Antibody (1D3)
H00004086-M02
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
Lysates
Smad1 Overexpression Lysate ( ...
Smad1 Overexpression Lysate (Native)
NBL1-16218
Applications: WB
Smad1 Overexpression Lysate ( ...
Smad1 Overexpression Lysate (Native)
NBL1-16219
Applications: WB
Smad1 Overexpression Lysate ( ...
Smad1 Overexpression Lysate (Denat...
H00004086-T01
Applications: WB
Proteins
Smad1 Recombinant Protein
Smad1 Recombinant Protein
H00004086-P01
Species: Hu
Applications: WB, ELISA, PA
Smad1 Partial Recombinant Pro ...
Smad1 Partial Recombinant Protein
H00004086-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
Smad1 RNAi
Smad1 RNAi
H00004086-R02
Species: Hu
Smad1 RNAi
Smad1 RNAi
H00004086-R01
Species: Hu

Description

Smad1 is encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 4086
Alternate Names
  • Smad1
  • Mad-related protein 1
  • transforming growth factor-beta signaling protein 1
  • MAD homolog 1
  • TGF-beta signaling protein 1
  • hSMAD1
  • SMAD, mothers against DPP homolog 1
  • BSP1
  • mothers against decapentaplegic homolog 1
  • BSP-1
  • mothers against decapentaplegic homolog 1
  • Mothers against DPP homolog 1
  • MADH1JV41
  • JV4-1SMAD, mothers against DPP homolog 1 (Drosophila)
  • MADR1MAD, mothers against decapentaplegic homolog 1 (Drosophila)
  • SMAD family member 1SMAD 1

Research Areas for Smad1

Find related products by research area and learn more about each of the different research areas below.

Cancer
Diabetes Research
Phospho-Specific

Bioinformatics Tool for Smad1

Discover related pathways, diseases and genes to Smad1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related Smad1 Blog Posts

Check out the latest blog posts on Smad1.
Nanog is a Master Controller of ES cell Pluripotency
Nanog, a homeodomain (HD) transcription factor, plays a critical role in the maintenance of embryonic stem (ES) cell self-renewal. Transcription regulator involved in inner cell mass and ES cell proliferation and self-renewal. Imposes pluripotency on...    Read more.
Transforming Growth Factor beta Signaling in Stem Cells
Transforming growth factor beta (TGF beta) signaling along with its family members have been implicated in development and maintenance of various organs. Stem cells are important contributors to this process and are characterized by their ability to s...    Read more.
Read more Smad1 related blogs.