SIN3B Products

Description

SIN3B acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA

Bioinformatics

Entrez	23309 Human
Uniprot	O75182 Human NP_056075 Human NP_056075.1 Human AAH63531.1 Human
Product By Gene ID	23309
Alternate Names	Transcriptional corepressor Sin3b SIN3 homolog B, transcriptional regulator Histone deacetylase complex subunit Sin3b KIAA0700paired amphipathic helix protein Sin3b SIN3 homolog B, transcriptional regulator (yeast) SIN3 homolog B, transcription regulator (yeast)

Diseases related to SIN3B

Discover more about diseases related to SIN3B.

Neoplasms
Malignant Neoplasms
Sudden Infant Death Syndrome
Cell Transformation, Neoplastic
Retinoblastoma
Hyperplasia
Malignant Neoplasm Of Breast
Carcinoma
Neuroblastoma
Leukemia
Neoplasm Metastasis
Non-neoplastic Disorder
Tumor Progression
Kidney Neoplasm
Olfactory Neuroblastoma
Leukemia, Myelocytic, Acute
Myeloid Leukemia
Nervousness
Renal Cell Carcinoma

Pathways for SIN3B

View related products by pathway and learn more about each of the pathways below.

Cell Cycle
Histone Acetylation
Histone Deacetylation
Cell Growth
Cell Cycle Arrest
Localization
Gene Silencing
Aging
Regulation Of Cell Cycle
Senescence
Transport
Response To Gamma Radiation
Cellular Senescence
Regulation Of Gene Expression
Spermatogenesis
Replicative Senescence
Flight
Response To Uv
Cell Differentiation
Oncogene-induced Senescence

PTMs for SIN3B

Learn more about PTMs related to SIN3B.

Acetylation
Deacetylation
Phosphorylation
Methylation
Ubiquitination

Bioinformatics Tool for SIN3B

Discover related pathways, diseases and genes to SIN3B. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.