SIAH2 Products

Antibodies
SIAH2 Antibody (24E6H3)
SIAH2 Antibody (24E6H3)
NB110-88113
Species: Hu, Po, Dr, Mu(-)
Applications: WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P
Host: Mouse Monoclonal
SIAH2 Antibody
SIAH2 Antibody
NBP1-19648
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
SIAH2 Antibody (1F5)
SIAH2 Antibody (1F5)
H00006478-M01
Species: Hu
Applications: ELISA
Host: Mouse Monoclonal
Lysates
SIAH2 Overexpression Lysate ( ...
SIAH2 Overexpression Lysate (Native)
NBL1-15955
Applications: WB
Proteins
Recombinant Human SIAH2 Prote ...
Recombinant Human SIAH2 Protein
H00006478-Q01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human SIAH2 Prote ...
Recombinant Human SIAH2 Protein
H00006478-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
SIAH2 RNAi
SIAH2 RNAi
H00006478-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

The Drosophila SINA (seven in absentia) protein is an E3 ubiquitin ligase component of the RAS signal transduction pathway. The RAS signal pathway controls cell proliferation, differentiation, and survival, and regulation of this pathway is critical for normal development. In Drosophila, SINA serves as a downstream gatekeeper required for proper RAS signal transduction. Similarly to SINA in Drosophila, the human protein SIAH has also been shown to be required for oncogenic RAS signaling in cancer.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 6478
Alternate Names
  • EC 6.3.2
  • E3 ubiquitin-protein ligase SIAH2
  • Seven in absentia homolog 2
  • Siah-2
  • seven in absentia (Drosophila) homolog 2
  • EC 6.3.2.-
  • hSiah2
  • siah-2
  • seven in absentia homolog 2 (Drosophila)

Research Areas for SIAH2

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Cell Cycle and Replication
Chromatin Modifiers
Chromatin Research
Hypoxia
Immunology
Ubiquitin Proteasome Pathway
Wnt Signaling Pathway

PTMs for SIAH2

Learn more about PTMs related to SIAH2.

Phosphorylation
Ubiquitination
Hydroxylation
Cleavage
Acetylation

Bioinformatics Tool for SIAH2

Discover related pathways, diseases and genes to SIAH2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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