Species: Hu, Mu, Rt
Applications: WB, IHC, ICC/IF
Host: Sheep Polyclonal
Host: Mouse Monoclonal
Applications: WB, ELISA, AP
Members of the semaphorin protein family are involved in axonal guidance during neural development. Semaphorin 5a is thought to have a bifunctional role in axon guidance, exerting both attractive and inhibitory effects on developing axons associated with limbic function. The thrombospondin repeats of Semaphorin 5a physically interact with both heparan sulfate proteoglycans and chondroitin sulfate proteoglycans, inducing attractive and inhibitory guidance cues, respectively. The biological responses to Semaphorin 5a are induced through binding to its high-affinity receptor, plexin B3, triggering intracellular signaling through Met.
|Product By Gene ID
- Sema F
- semaphorin F
- transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
- sema domain, seven thrombospondin repeats (type 1 and type 1-like)
PTMs for Semaphorin 5A
Learn more about PTMs related to Semaphorin 5A.Phosphorylation
Bioinformatics Tool for Semaphorin 5A
Discover related pathways, diseases and genes to Semaphorin 5A. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.