Species: Hu
Applications: IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Bv, Ca
Applications: ELISA, IHC
Host: Goat Polyclonal
Species: Hu, Mu, Rt
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Bioactivity
Species: Mu
Applications: Bioactivity
Species: Hu
Applications: AC
Description
Members of the semaphorin protein family are involved in axonal guidance during neural development. Semaphorin 5a is thought to have a bifunctional role in axon guidance, exerting both attractive and inhibitory effects on developing axons associated with limbic function. The thrombospondin repeats of Semaphorin 5a physically interact with both heparan sulfate proteoglycans and chondroitin sulfate proteoglycans, inducing attractive and inhibitory guidance cues, respectively. The biological responses to Semaphorin 5a are induced through binding to its high-affinity receptor, plexin B3, triggering intracellular signaling through Met.
Bioinformatics
| Entrez |
Mouse
Rat
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
9037 |
| Alternate Names |
- FLJ12815
- sema domain, seven thrombospondin repeats (type 1 and type 1-like)
- Sema F
- SEMAF
- semaphorin F
- semaphorin-5A
- semaphorin-F
- Semaphorin-F
- semF
- SEMF
- transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
|
![Immunohistochemistry Semaphorin 5A Antibody (914419) [Unconjugated]](http://images.novusbio.com/fullsize2/Semaphorin_5A_MAB5896_Immunohistochemistry_16830.jpg)
