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HAF005). A specific band for Semaphorin 4D/CD100 was detected at approximately 115 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1." class="big_lightbox" target="_blank">
Semaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development. CD100, a 150 kDa homodimer, is a novel semaphorin that induces B cells to aggregate and improves their viability in vitro. CD100 modifies CD40-CD40L B cell signaling by augmenting B cell aggregation and survival and down regulating CD23 expression. CD72 is a lymphocyte receptor for the class IV semaphorin CD100, which is involved in regulating B cell signaling. CD100 is expressed on resting and PHA stimulated T cells. The protein is weakly expressed on NK cells, EBV transformed B cells, monocytes and tumor/peripheral blood T cell lines, and at higher density on activated T cells and B cells.
![Flow Cytometry Semaphorin 4D/CD100 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/Semaphorin_4D_AF5235_Flow_Cytometry_8267.jpg)
![Sandwich ELISA Semaphorin 4D/CD100 Antibody Pair [HRP]](http://images.novusbio.com/fullsize/Semaphorin-4D-CD100-Antibody-Pair-[HRP]-Sandwich-ELISA-NBP2-79597-img0001.jpg)
![Immunohistochemistry Semaphorin 4D/CD100 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/Semaphorin_4D_AF5235_Immunohistochemistry_24184.jpg)
