SCNN1D Products

Antibodies
SCNN1D Antibody
SCNN1D Antibody
NBP1-85004
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
SCNN1D Antibody
SCNN1D Antibody
NBP2-20271
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
SCNN1D Antibody
SCNN1D Antibody
H00006339-D01P
Species: Hu
Applications: WB, ELISA
Host: Rabbit Polyclonal
Lysates
SCNN1D Overexpression Lysate ...
SCNN1D Overexpression Lysate (Native)
NBP2-08053
Applications: WB
SCNN1D Overexpression Lysate ...
SCNN1D Overexpression Lysate (Dena...
H00006339-T02
Applications: WB
Proteins
SCNN1D Partial Recombinant Pr ...
SCNN1D Partial Recombinant Protein
H00006339-Q01
Species: Hu
Applications: WB, ELISA, PA
SCNN1D Recombinant Protein An ...
SCNN1D Recombinant Protein Antigen
NBP1-85004PEP
Species: Hu
Applications: AC
RNAi
SCNN1D RNAi
SCNN1D RNAi
H00006339-R01
Species: Hu

Description

SCNN1D is a subunit of the epithelial sodium channel (ENaC). ENaC has high sodium selectivity, low conductance, and amiloride sensitivity. The epithelial Na(+) channel (ENaC) regulates Na(+) homeostasis in cells and across epithelia; in the kidney, lung and colon it plays an essential role in trans-epithelial sodium and fluid balance. ENaC also mediates aldosterone-dependent sodium re-uptake in the distal nephron of the kidney, thus regulating blood pressure. Four homologous ENaC subunits (alpha, beta, gamma, and delta) have been isolated in mammals. Combination of alpha-, beta-, and gamma-subunits or delta-, beta-, and gamma-subunits forms fully functional channels. A delta subunit can replace the alpha subunit. However, the pharmacology, sensitivity to amiloride, conductance, and ionic selectivity of the delta/beta-gamma channel are different from those of the alpha/beta-gamma channel. FUNCTION: Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. SUBUNIT: Heterotetramer of two alpha, one beta and one gamma subunit. A delta subunit can replace the alpha subunit. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.

Bioinformatics

Entrez Human
Uniprot Human
Product By Gene ID 6339
Alternate Names
  • ENaCD
  • MGC149711
  • Delta-NaCH
  • MGC149710
  • Delta-ENaC
  • ENaCd
  • DNACH
  • SCNED
  • voltage-gated, type I, delta polypeptide
  • sodium channel, nonvoltage-gated 1, delta

Pathways for SCNN1D

View related products by pathway and learn more about each of the pathways below.

Transport
Sperm Motility
Cell Cycle
Pathogenesis
Localization
Cell Cycle Arrest
Secretion

PTMs for SCNN1D

Learn more about PTMs related to SCNN1D.

Phosphorylation

Bioinformatics Tool for SCNN1D

Discover related pathways, diseases and genes to SCNN1D. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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