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RUNX3/CBFA3 Products

Antibodies
RUNX3/CBFA3 Antibody (2B3) - ...
RUNX3/CBFA3 Antibody (2B3) - BSA Free
NBP2-37455
Species: Hu, Mu
Applications: WB, ELISA, Flow, ICC/IF, IHC, CyTOF-ready
Host: Mouse Monoclonal
Formulation Catalog # Availability Price  
Lysates
RUNX3/CBFA3 Overexpression Ly ...
RUNX3/CBFA3 Overexpression Lysate
NBL1-15629
Species: Hu
Applications: WB
Proteins
Recombinant Human RUNX3/CBFA3 ...
Recombinant Human RUNX3/CBFA3 His ...
NBP1-44462
Species: Hu
Applications: PAGE
RUNX3/CBFA3 Recombinant Prote ...
RUNX3/CBFA3 Recombinant Protein An...
NBP2-38863PEP
Species: Hu
Applications: AC

Description

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Bioinformatics

Entrez Human
Uniprot Human
Product By Gene ID 864
Alternate Names
  • Acute myeloid leukemia 2 protein
  • AML2
  • AML2SL3/AKV core-binding factor alpha C subunit
  • CBFA3
  • CBFA3MGC16070
  • CBF-alpha-3
  • PEA2 alpha C
  • PEA2-alpha C
  • PEBP2 alpha C
  • PEBP2A3
  • PEBP2A3FLJ34510
  • PEBP2AC
  • PEBP2-alpha C
  • runt domain, alpha subunit 3
  • runt-related transcription factor 3
  • RUNX3
  • SL3-3 enhancer factor 1 alpha C subunit
  • transcription factor AML2

Research Areas for RUNX3/CBFA3

Find related products by research area and learn more about each of the different research areas below.

Transcription Factors and Regulators