Species: Mu
Applications: WB
Host: Goat Polyclonal
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
Species: Hu
Applications: AC
Description
The protein encoded by the GLIPR1 gene works as a proapoptic initiator in prostate and bladder cells. Not all variants of the GLIPR1 gene have been documented even though multiple isoforms have been described (isoform 1: 255 AA long, 30 kDA; isoform 2: 237 AA long, nearly 30 kDA). The glioma pathogenesis-related protein 1 provided by the GLIPR1 gene is related to both the pathogenesis-related protein (PR) superfamily as well as the cysteine-rich secretory protein (CRISP) family. GLIPR1 has been research regarding its role in Wilms tumors, neuronitis, prostatitis, leukemia, glioblastoma, astrocytoma where increased expression has been linked with myelomocytic differentiation in macrophage and decreased expression (through gene methylation) has been associated to prostate cancer. The GLIPR1 gene interacts with genes CHD9, NCOA2, NCOA6, CREBBP, and CARM1 to participate in metabolism, expression of GLIPR1 and PPARA activation gene expression.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human |
Product By Gene ID |
11010 |
Alternate Names |
- GLI pathogenesis-related 1 (glioma)
- GLI pathogenesis-related 1
- GliPR 1
- GliPR
- GLIPRglioma pathogenesis-related protein 1
- Protein RTVP-1
- related to testis-specific, vespid, and pathogenesis proteins 1
- RTVP1CRISP7
- testes-specific vespid and pathogenesis protein 1
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