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Roquin Products

Antibodies
Roquin Antibody - BSA Free
Roquin Antibody - BSA Free
NBP1-89589
Species: Hu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
Lysates
Roquin Overexpression Lysate
Roquin Overexpression Lysate
NBP2-05190
Species: Hu
Applications: WB
Proteins
Roquin Recombinant Protein An ...
Roquin Recombinant Protein Antigen
NBP1-89591PEP
Species: Hu
Applications: AC
Roquin Recombinant Protein An ...
Roquin Recombinant Protein Antigen
NBP1-89589PEP
Species: Hu
Applications: AC
Roquin Recombinant Protein An ...
Roquin Recombinant Protein Antigen
NBP1-89590PEP
Species: Hu
Applications: AC

Description

Roquin is a member of the RING-type E3 ubiquitin ligase protein family. It was recently found to contribute to autoimmune diseases such as type 1 diabetes and lupus. Research has found that a mutation in roquin causes T-cells to attack their own tissues. Roquin stops T-cells from displaying a stimulatory receptor, ICOS, that may cause the cells to attack normal body tissues. (1)

Bioinformatics

Entrez Human
Uniprot Human
Product By Gene ID 149041
Alternate Names
  • KIAA2025RP5-1198E17.5
  • RING finger and C3H zinc finger protein 1
  • ring finger and CCCH-type domains 1
  • RING finger protein 198
  • RNF198ring finger and CCCH-type zinc finger domains 1
  • roquin

Research Areas for Roquin

Find related products by research area and learn more about each of the different research areas below.

Immunology