RGS18 Products

Description

This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Bioinformatics

Entrez	64407 Human
Uniprot	AAH20632 Human
Product By Gene ID	64407
Alternate Names	regulator of G-protein signaling 18 regulator of G-protein signalling 13 RGS13regulator of G-protein signalling 18

Research Areas for RGS18

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction