Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, IP
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Po, Bv, Ca, Rb
Applications: WB, ELISA
Host: Goat Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Description
RFX5 is the regulatory gene responsible for human MHC class II deficiency. Patients with this disease exhibit a characteristic defect in the binding of a nuclear factor, RFX, to the X box motif of MHC class II promoters. RFX5 is the 75 kDa subunit of the RFX complex which is absolutely essential and highly specific for regulating MHC class II gene expression and control of the immune response. RFX5 is a protein consisting of 616 amino acids.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human Human |
Product By Gene ID |
5993 |
Alternate Names |
- DNA-binding protein RFX5
- Regulatory factor X 5
- regulatory factor X, 5 (influences HLA class II expression)
|
Research Areas for RFX5
Find related products by research area and learn more about each of the different research areas below.
Adaptive ImmunityImmunology