RFX5 Products

Description

RFX5 is the regulatory gene responsible for human MHC class II deficiency. Patients with this disease exhibit a characteristic defect in the binding of a nuclear factor, RFX, to the X box motif of MHC class II promoters. RFX5 is the 75 kDa subunit of the RFX complex which is absolutely essential and highly specific for regulating MHC class II gene expression and control of the immune response. RFX5 is a protein consisting of 616 amino acids.

Bioinformatics

Entrez	5993 Human
Uniprot	NM_000449 Human NP_000440 Human NP_000440.1 Human NP_001020774 Human
Product By Gene ID	5993
Alternate Names	DNA-binding protein RFX5 Regulatory factor X 5 regulatory factor X, 5 (influences HLA class II expression)

Research Areas for RFX5

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Immunology