retinol dehydrogenase 8 (all trans) Products

Lysates
retinol dehydrogenase 8 (all ...
retinol dehydrogenase 8 (all trans...
NBP2-07124
Applications: WB
retinol dehydrogenase 8 (all ...
retinol dehydrogenase 8 (all trans...
H00050700-T01
Species: Hu
Applications: WB
Proteins
Recombinant Human retinol deh ...
Recombinant Human retinol dehydrog...
H00050700-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
retinol dehydrogenase 8 (all ...
retinol dehydrogenase 8 (all trans...
H00050700-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

All-trans-retinol dehydrogenase (RDH8) is a visual cycle enzyme that reduces all-trans-retinal to all-trans-retinol in the presence of NADPH (Rattner et al., 2000 [PubMed 10753906]). It is a member of the short chain dehydrogenase/reductase family and is located in the outer segments of photoreceptors; hence it is also known as photoreceptor retinol dehydrogenase. It is important in the visual cycle by beginning the rhodopsin regeneration pathway by reducing all-trans-retinal, the product of bleached and hydrolysed rhodopsin (Rando, 2001 [PubMed 11710234]). This is a rate-limiting step in the visual cycle (Saari et al., 1998 [PubMed 9667000]).[supplied by OMIM]

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 50700
Alternate Names
  • retinol dehydrogenase 8
  • PRRDH
  • short chain dehydrogenase/reductase family 28C, member 2
  • photoreceptor outer segment all-trans retinol dehydrogenase
  • SDR28C2
  • retinol dehydrogenase 8 (all-trans)

Pathways for retinol dehydrogenase 8 (all trans)

View related products by pathway and learn more about each of the pathways below.

Cell Death
Regeneration
Metabolic Process
Pathogenesis
Localization

PTMs for retinol dehydrogenase 8 (all trans)

Learn more about PTMs related to retinol dehydrogenase 8 (all trans).

Oxidation

Bioinformatics Tool for retinol dehydrogenase 8 (all trans)

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