RAPGEF2 Products

Description

Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF2, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM]

Bioinformatics

Entrez	9693 Human
Uniprot	Q9Y4G8 Human
Product By Gene ID	9693
Alternate Names	CNrasGEF KIAA0313 Neural RAP guanine nucleotide exchange protein nRap GEP NRAPGEP PDZ domain containing guanine nucleotide exchange factor (GEF) 1 PDZGEF1 PDZ-GEF1PDZ domain-containing guanine nucleotide exchange factor 1 RA(Ras/Rap1A-associating)-GEF RA-GEFDKFZP586O1422 Rap guanine nucleotide exchange factor (GEF) 2 rap guanine nucleotide exchange factor 2 Rap-GEP

Research Areas for RAPGEF2

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction