RAP80 Products

Antibodies
RAP80 Antibody
RAP80 Antibody
NBP1-87156
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
RAP80 Antibody
RAP80 Antibody
NB100-2347
Species: Hu, Primate
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
RAP80 Antibody
RAP80 Antibody
NBP1-87157
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Antibody Pairs
RAP80 Antibody Pair
RAP80 Antibody Pair
H00051720-PW1
Species: Hu
Applications: WB, IP
Lysates
RAP80 Overexpression Lysate ( ...
RAP80 Overexpression Lysate (Native)
NBP2-07057
Applications: WB
RAP80 Overexpression Lysate ( ...
RAP80 Overexpression Lysate (Denat...
H00051720-T01
Species: Hu
Applications: WB
Proteins
RAP80 Recombinant Protein
RAP80 Recombinant Protein
H00051720-P01
Species: Hu
Applications: WB, ELISA, PA
RAP80 Recombinant Protein Ant ...
RAP80 Recombinant Protein Antigen
NBP1-87157PEP
Species: Hu
Applications: AC
RAP80 Recombinant Protein Ant ...
RAP80 Recombinant Protein Antigen
NBP1-87156PEP
Species: Hu
Applications: AC

Description

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. TRAP80 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. TRAP80 is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This antibody was raised by a genetic immunization technique. Genetic immunization can be used to generate antibodies by directly delivering antigen-coding DNA into the animal, rather than injecting a protein or peptide (Tang et al. PubMed: 1545867; Chambers and Johnston PubMed 12910245; Barry and Johnston PubMed: 9234514). The animals cells produce the protein, which stimulates the animals immune system to produce antibodies against that particular protein. A vector coding for a partial fusion protein was used for genetic immunisation of a mouse and the resulting serum was tested in Western blot against an E.coli lysate containing that partial fusion protein. Genetic immunization offers enormous advantages over the traditional protein-based immunization method. DNA is faster, cheaper and easier to produce and can be produced by standard techniques readily amenable to automation. Furthermore, the antibodies generated by genetic immunization are usually of superior quality with regard to specificity, affinity and recognizing the native protein.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 51720
Alternate Names
  • RXRIP110
  • retinoid x receptor interacting protein
  • Ubiquitin interaction motif-containing protein 1
  • receptor associated protein 80
  • Retinoid X receptor-interacting protein 110
  • BRCA1-A complex subunit RAP80
  • Receptor-associated protein 80
  • RAP80X2HRIP110
  • ubiquitin interaction motif containing 1

Diseases related to RAP80

Discover more about diseases related to RAP80.

Malignant Neoplasms
Cardiovascular Diseases
Neoplasms
Malignant Neoplasm Of Breast

Pathways for RAP80

View related products by pathway and learn more about each of the pathways below.

Menopause
Histone Ubiquitination
Dna Repair
Menarche

Research Areas for RAP80

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Cancer

PTMs for RAP80

Learn more about PTMs related to RAP80.

Ubiquitination

Bioinformatics Tool for RAP80

Discover related pathways, diseases and genes to RAP80. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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